First time used, the doctors noticed it had very little affect on angina, but noticed in had an affect on penile erections
Pfizer then decided to market it for erectile dysfunction instead of angina
The drug was patented in 1996, approved for use in erectile dysfunction by the FDA
Melting Point and Boiling Point
Melting Point- 189-190 °C
Boiling Point- 672.4 °C
Where is it found/Obtained Sildenafil is found in the erectile dysfunction drug Viagra. It is only able to be obtained by prescription from a doctor, so therefore you need a prescription to obtain it. Although it was first used to find a cure for hypertension and angina pectoris, it is only used now for erectile dysfunction.Uses and Importances
Sildenafil is used in the erectile dysfunction drug Viagra. The interesting fact about this though is that it was not first invented for this cause. It was originally invented for the cure for angina pectoris and hypertension. These both have to do with high blood pressure and severe chest pains. When Pfizer (creator of Sildenafil) injected it into his patient, he realized it didn't help ease the pain in the chest, but it caused the patient to develop an erection. From there on out he continued his study on the drug and realized the effect it had on older men, it helped cause their ED.
Explanation of Structure
The percent composition of Sildenafil is as follows: C=59.70%, H=6.833%, O=14.46%, and N=18.99%
Percent Composition by number is as follows: C=35.48%, H=48.38%, O=9.67%, N=6.45%
By: Jake
Formula- C22H30N6O4S
Molar Mass- 474.6 g/mol
IUPAC Name- 1-[4-ethoxy-3-(6,7-dihydro-1-methyl-
7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)
phenylsulfonyl]-4-methylpiperazine citrate
Historical Background
Melting Point and Boiling Point
Melting Point- 189-190 °C
Boiling Point- 672.4 °C
Where is it found/Obtained
Sildenafil is found in the erectile dysfunction drug Viagra. It is only able to be obtained by prescription from a doctor, so therefore you need a prescription to obtain it. Although it was first used to find a cure for hypertension and angina pectoris, it is only used now for erectile dysfunction. Uses and Importances
Sildenafil is used in the erectile dysfunction drug Viagra. The interesting fact about this though is that it was not first invented for this cause. It was originally invented for the cure for angina pectoris and hypertension. These both have to do with high blood pressure and severe chest pains. When Pfizer (creator of Sildenafil) injected it into his patient, he realized it didn't help ease the pain in the chest, but it caused the patient to develop an erection. From there on out he continued his study on the drug and realized the effect it had on older men, it helped cause their ED.
Explanation of Structure
The percent composition of Sildenafil is as follows: C=59.70%, H=6.833%, O=14.46%, and N=18.99%
Percent Composition by number is as follows: C=35.48%, H=48.38%, O=9.67%, N=6.45%
CitationsWebites
- "Sildenafil". Wikipedia. 11/17/09 http://en.wikipedia.org/wiki/Sildenafil.
- "Medications and Drugs". MedicineNet. 11/17/09 <http://www.medicinenet.com/sildenafil/article.htm>.
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